Treinamento físico e níveis hormonais em homens adultos jovens: uma revisão sistemática
REF / JPE 2025 94, 2
pdf

Palavras-chave

testosterona
sáude
promoção da saúde
treinamento físico
sistema endócrino

Como Citar

Santiago, L. Ângelo M., Matos, C. de B., Serra, H. C. A., Tupiná, G. P., & Neto, D. C. A. (2025). Treinamento físico e níveis hormonais em homens adultos jovens: uma revisão sistemática. Revista De Educação Física / Journal of Physical Education, 94(2), 421–434. https://doi.org/10.37310/ref.v94i2.3086

Resumo

Introdução: Hormônios andrógenos desempenham um papel importante na saúde do homem. Sua deficiência inicia-se gradualmente a partir dos 30 anos de idade, trazendo sintomas físicos e impacto na qualidade de vida. Em contrapartida, a prática de exercícios físicos é uma das principais estratégias não farmacológicas que promovem a saúde e o bem-estar, trazendo benefícios para massa muscular e composição corporal devido a regulação dos níveis hormonais.

Objetivo: Investigar os efeitos do exercício físico nos níveis hormonais em homens adultos jovens.

Métodos: Trata-se de uma revisão integrativa com abordagem qualitativa, de natureza descritiva e exploratória da literatura. Os acervos eletrônicos e Periódicos da Biblioteca Virtual em Saúde (BVS), PubMed, Web of Science e SPORTDiscus, sendo as três últimas acessadas por meio do Portal de Periódicos da Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES) foram consultados para buscar estudos de intervenção sobre marcadores hormonais vs treinamento resistido/combinado e aeróbio em homens adultos jovens, publicados entre 2020 e 2024 com faixa etária de 20 a 26 anos e escritos em português ou inglês.

Resultados e Discussão: Exercício físico quando planejado, estruturado e repetitivo eleva os níveis de testosterona e IGF-1 em homens adultos jovens e dependem da combinação de intensidade e volume dos programas para promover benefícios tanto para a aptidão física quanto para a saúde endócrina.

Conclusão: Os estudos incluídos nessa revisão reforçam o papel do exercício físico como estratégia não farmacológica para a promoção da saúde masculina, destacando os efeitos a curto e longo prazo sobre o eixo hormonal.

https://doi.org/10.37310/ref.v94i2.3086
pdf

Referências

Stárka L, Dušková M. What is a hormone? Physiological Research. 2020;69(Suppl 2): S183–S185. https://doi.org/10.33549/physiolres.934509.

Aref Y, Fat SC, Ray E. Recent insights into the role of hormones during development and their functional regulation. Frontiers in Endocrinology. 2024;15: 1340432. https://doi.org/10.3389/fendo.2024.1340432.

Alemany M. The Roles of Androgens in Humans: Biology, Metabolic Regulation and Health. International Journal of Molecular Sciences. 2022;23(19): 11952. https://doi.org/10.3390/ijms231911952.

Smith LB, Walker WH. The regulation of spermatogenesis by androgens. Seminars in Cell & Developmental Biology. 2014;30: 2–13. https://doi.org/10.1016/j.semcdb.2014.02.012.

Naamneh Elzenaty R, du Toit T, Flück CE. Basics of androgen synthesis and action. Best Practice & Research. Clinical Endocrinology & Metabolism. 2022;36(4): 101665. https://doi.org/10.1016/j.beem.2022.101665.

Oduwole OO, Huhtaniemi IT, Misrahi M. The Roles of Luteinizing Hormone, Follicle-Stimulating Hormone and Testosterone in Spermatogenesis and Folliculogenesis Revisited. International Journal of Molecular Sciences. 2021;22(23): 12735. https://doi.org/10.3390/ijms222312735.

Zitzmann M. Testosterone, mood, behaviour and quality of life. Andrology. 2020;8(6): 1598–1605. https://doi.org/10.1111/andr.12867.

Anawalt BD, Matsumoto AM. Aging and androgens: Physiology and clinical implications. Reviews in Endocrine & Metabolic Disorders. 2022;23(6): 1123–1137. https://doi.org/10.1007/s11154-022-09765-2.

Grgic J, Garofolini A, Orazem J, Sabol F, Schoenfeld BJ, Pedisic Z. Effects of Resistance Training on Muscle Size and Strength in Very Elderly Adults: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Sports Medicine (Auckland, N.Z.). 2020;50(11): 1983–1999. https://doi.org/10.1007/s40279-020-01331-7.

Štursová P, Budinská X, Nováková Z, Dobšák P, Babula P. Sports activities and cardiovascular system change. Physiological Research. 2023;72(S5): S429–S444. https://doi.org/10.33549/physiolres.935238.

Jansson D, Lindberg AS, Lundberg E, Domellöf M, Theos A. Effects of Resistance and Endurance Training Alone or Combined on Hormonal Adaptations and Cytokines in Healthy Children and Adolescents: A Systematic Review and Meta-analysis. Sports Medicine - Open. 2022;8(1): 81. https://doi.org/10.1186/s40798-022-00471-6.

Silva AF, Aghidemand MH, Kharatzadeh M, Ahmadi VK, Oliveira R, Clemente FM, et al. Effects of High-Intensity Resistance Training on Physical Fitness, Hormonal and Antioxidant Factors: A Randomized Controlled Study Conducted on Young Adult Male Soccer Players. Biology. 2022;11(6): 909. https://doi.org/10.3390/biology11060909.

Dote‐Montero M, Carneiro‐Barrera A, Martinez‐Vizcaino V, Ruiz JR, Amaro‐Gahete FJ. Acute effect of HIIT on testosterone and cortisol levels in healthy individuals: A systematic review and meta‐analysis. Scandinavian Journal of Medicine & Science in Sports. 2021;31(9): 1722–1744. https://doi.org/10.1111/sms.13999.

Ambroży T, Rydzik Ł, Obmiński Z, Błach W, Serafin N, Błach B, et al. The Effect of High-Intensity Interval Training Periods on Morning Serum Testosterone and Cortisol Levels and Physical Fitness in Men Aged 35–40 Years. Journal of Clinical Medicine. 2021;10(10): 2143. https://doi.org/10.3390/jcm10102143.

Ma N, Gao F. Correlation between low testosterone levels and the risk of osteoarthritis: a cross-sectional analysis of NHANES data (2011-2016). BMC musculoskeletal disorders. 2025;26(1): 23. https://doi.org/10.1186/s12891-024-08272-6.

Negretto LAF, Rassi N, Soares LR, Saraiva ABC, Teixeira MEF, Santos L da R, et al. Deficiência de Testosterona em Homens Hipertensos: Prevalência e Fatores Associados. Arquivos Brasileiros de Cardiologia. 2024;121: e20230138. https://doi.org/10.36660/abc.20230138.

Macedo AG, Bernardino Da Silva A, De Oliveira DM, Simionato AR, Goes ATR, Muller Pessôa Filho D. Treinamento resistido e sistema endócrino: revisão de literatura. Itinerarius Reflectionis. 2020;16(3): 01–15. https://doi.org/10.5216/rir.v16i3.58190.

De Alcantara Borba D, Da Silva Alves E, Rosa JPP, Facundo LA, Costa CMA, Silva AC, et al. Can IGF-1 Serum Levels Really be Changed by Acute Physical Exercise? A Systematic Review and Meta-Analysis. Journal of Physical Activity and Health. 2020;17(5): 575–584. https://doi.org/10.1123/jpah.2019-0453.

Yoshida T, Delafontaine P. Mechanisms of IGF-1-Mediated Regulation of Skeletal Muscle Hypertrophy and Atrophy. Cells. 2020;9(9): 1970. https://doi.org/10.3390/cells9091970.

Macvanin M, Gluvic Z, Radovanovic J, Essack M, Gao X, Isenovic ER. New insights on the cardiovascular effects of IGF-1. Frontiers in Endocrinology. 2023;14: 1142644. https://doi.org/10.3389/fendo.2023.1142644.

Larsson SC, Michaëlsson K, Burgess S. IGF-1 and cardiometabolic diseases: a Mendelian randomisation study. Diabetologia. 2020;63(9): 1775–1782. https://doi.org/10.1007/s00125-020-05190-9.

Stern C, Jordan Z, McArthur A. Developing the review question and inclusion criteria. The American Journal of Nursing. 2014;114(4): 53–56. https://doi.org/10.1097/01.NAJ.0000445689.67800.86.

Ursi ES, Gavão CM. Prevenção de lesões de pele no perioperatório: revisão integrativa da literatura. Revista Latino-Americana de Enfermagem. 2006;14: 124–131. https://doi.org/10.1590/S0104-11692006000100017.

Page MJ, McKenzie JE, Bossuyt PM, Boutron I, Hoffmann TC, Mulrow CD, et al. The PRISMA 2020 statement: an updated guideline for reporting systematic reviews. BMJ. 2021; n71. https://doi.org/10.1136/bmj.n71.

Bemben DA, Sherk VD, Buchanan SR, Kim S, Sherk K, Bemben MG. Acute and Chronic Bone Marker and Endocrine Responses to Resistance Exercise With and Without Blood Flow Restriction in Young Men. Frontiers in Physiology. 2022;13: 837631. https://doi.org/10.3389/fphys.2022.837631.

Studencki M, Ignatjeva A, Nitychoruk M, Gołaś A, Smółka W, Maszczyk A. Effect of bench press at a specified movement tempo on post-exercise testosterone and cortisol levels. Physical Activity Review. 2021;9(2): 111–119. https://doi.org/10.16926/par.2021.09.27.

Laurentino G, Loenneke J, Ugrinowitsch C, Aoki M, Soares A, Roschel H, et al. Blood-Flow-Restriction-Training-Induced Hormonal Response is not Associated with Gains in Muscle Size and Strength. Journal of Human Kinetics. 2022;83: 235–243. https://doi.org/10.2478/hukin-2022-0095.

Vilaça-Alves J, Magalhães PS, Rosa CV, Reis VM, Garrido ND, Payan-Carreira R, et al. Acute Hormonal Responses to Multi-Joint Resistance Exercises with Blood Flow Restriction. Journal of Functional Morphology and Kinesiology. 2022;8(1): 3. https://doi.org/10.3390/jfmk8010003.

Chycki J, Krzysztofik M, Sadowska-Krępa E, Baron-Kaczmarek D, Zając A, Poprzęcki S, et al. Acute Hormonal and Inflammatory Responses following Lower and Upper Body Resistance Exercises Performed to Volitional Failure. International Journal of Molecular Sciences. 2024;25(13): 7455. https://doi.org/10.3390/ijms25137455.

Räntilä A, Ahtiainen JP, Häkkinen K. Effects of Acute Loading Induced Fatigability, Acute Serum Hormone Responses and Training Volume to Individual Hypertrophy and Maximal Strength during 10 Weeks of Strength Training. Journal of Sports Science and Medicine. 2023; 559–570. https://doi.org/10.52082/jssm.2023.559.

Johnson TK, Belcher DJ, Sousa CA, Carzoli JP, Visavadiya NP, Khamoui AV, et al. Low-volume acute multi-joint resistance exercise elicits a circulating brain-derived neurotrophic factor response but not a cathepsin B response in well-trained men. Applied Physiology, Nutrition, and Metabolism. 2020;45(12): 1332–1338. https://doi.org/10.1139/apnm-2019-0854.

Vechin FC, Vingren JL, Telles GD, Conceicao MS, Libardi CA, Lixandrao ME, et al. Acute changes in serum and skeletal muscle steroids in resistance-trained men. Frontiers in Endocrinology. 2023;14: 1081056. https://doi.org/10.3389/fendo.2023.1081056.

Ghobadi H, Rashidlamir A, Mohammad Rahimi GR. Anabolic myokine responses and muscular performance following 8 weeks of autoregulated compared to linear resistance exercise in recreationally active males. Hormones. 2024;23(3): 487–496. https://doi.org/10.1007/s42000-024-00544-z.

Pareja-Blanco F, Rodríguez-Rosell D, Aagaard P, Sánchez-Medina L, Ribas-Serna J, Mora-Custodio R, et al. Time Course of Recovery From Resistance Exercise With Different Set Configurations. Journal of Strength and Conditioning Research. 2020;34(10): 2867–2876. https://doi.org/10.1519/JSC.0000000000002756.

Miranda H, De Souza JAAA, Scudese E, Paz GA, Salerno VP, Vigário PDS, et al. Acute Hormone Responses Subsequent to Agonist-Antagonist Paired Set vs. Traditional Straight Set Resistance Training. Journal of Strength and Conditioning Research. 2020;34(6): 1591–1599. https://doi.org/10.1519/JSC.0000000000002633.

Kizilay F, Emin Kafkas M, Çağatay Taşkapan M, Haydar Demirel A, Radak Z. Impact of differing eccentric-concentric phase durations on muscle damage and anabolic hormones. Isokinetics and Exercise Science. 2024;32(1): 29–39. https://doi.org/10.3233/IES-220078.

Vajda M, Vanderka M, Buzgó G, Sedliak M, Kampmiller T. The effect of different training modalities on resting hormonal level in active young males. Journal of Applied Biomedicine. 2021;19(2): 83–90. https://doi.org/10.32725/jab.2021.008.

Zurek G, Danek N, Żurek A, Nowak-Kornicka J, Żelaźniewicz A, Orzechowski S, et al. Effects of Dominance and Sprint Interval Exercise on Testosterone and Cortisol Levels in Strength-, Endurance-, and Non-Training Men. Biology. 2022;11(7): 961. https://doi.org/10.3390/biology11070961.

Ge RS, Li X, Wang Y. Leydig Cell and Spermatogenesis. In: Cheng CY, Sun F (eds) Molecular Mechanisms in Spermatogenesis. Cham: Springer International Publishing; 2021. p. 111–129. https://doi.org/10.1007/978-3-030-77779-1_6. [Accessed 11th November 2025].

Rojas-Zambrano JG, Rojas-Zambrano AR, Rojas-Zambrano AF, Barahona-Cueva GE. Benefits of Testosterone Hormone in the Human Body: A Systematic Review. Cureus. 17(2): e78785. https://doi.org/10.7759/cureus.78785.

Pryor JL, Sweet DK, Rosbrook P, Qiao J, Looney DP, Mahmood S, et al. Endocrine Responses to Heated Resistance Exercise in Men and Women. Journal of Strength and Conditioning Research. 2024;38(7): 1248–1255. https://doi.org/10.1519/JSC.0000000000004768.

Potter NJ, Tomkinson GR, Dufner TJ, Walch TJ, Roemmich JN, Wilson PB, et al. Effects of Exercise Training on Resting Testosterone Concentrations in Insufficiently Active Men: A Systematic Review and Meta-Analysis. Journal of Strength & Conditioning Research. 2021;35(12): 3521–3528. https://doi.org/10.1519/JSC.0000000000004146.

Creative Commons License
Este trabalho está licenciado sob uma licença Creative Commons Attribution 4.0 International License.

Copyright (c) 2025 Revista de Educação Física / Journal of Physical Education